David Kupfer smiles


From the NEDMDG Symposia


2008
Fall Dinner Meeting, 10 Sep 2008
Metabolites and Safety: Diligence on Safety - Expedience for Patients - scott-obach.pdf (124 KB)

Summer Symposium, 4 Jun 2008
Biomarkers and Translational Medicine - donna-mendrick.pdf (3.86 MB)

Novel Translational Biomarkers - peter-obrien.pdf (2.53 MB)

Regulatory Application of Quantitative Analysis: Impact of Biomarker Data - yaning-wang.ppt (1.86 MB)

Application of PK/PD Modeling for Developing and Evaluating Rational Strategies for Optimizing Therapy with Mabs - joseph-balthasar.pdf (0.60 MB)

Using Biomarkers for Early Phase Dose Selection with Protein Antagonist Drugs - ivan-nestorov.ppt (1.71 MB)


Spring Meeting, 12 Mar 2008
The Economics of New Drug Development:
Costs, Risks and Returns - joseph-dimasi-spring-2008.ppt (612 KB)



2007

























Download all presentations (10.60 MB, .zip)
Dinner Meeting, 5 Dec 2007
In Vitro to In Vivo Predictions of Drug Interactions:
Going Beyond the I/Ki Ratio - jash-unadkat.pdf (1.20 MB)


Gerald Miwa Retirement Symposium, 9 Apr 2007
DMPK in drug industry: The challenges of dealing with promiscuous drug-metabolizing enzymes, receptors and transporters
- anthony-lu.pdf (2.10 MB)

SUSTIVA: Uncovering the mechanism for the metabolism-dependent, species-selective nephrotoxicity - david-christ.pdf (0.50 MB)

DM/PK-guided lead optimization: A historical perspective of a paradigm shift - dhiren-thakker.pdf (0.60 MB)

P450 reactions: The basic, the exotic and the important
- fred-guengerich.pdf (3.00 MB)

Memories from a career - gerald-miwa.pdf (3.60 MB)

Heme: the catalytic center and a target in hemoproteins
- paul-ortiz.pdf (1.16 MB)

Predicting DMPK of NMEs: What Do We Need in Terms of Science and Tools? - leslie-benet.pdf (0.60 MB )

Human Metabolism of a Novel Chemotherapeutic: Illuminating the Mechanisms of P450-Catalyzed Deboronation - scott-daniels.pdf (0.60 MB)



2006


Current perspectives on Rapid INDs - mitch-cayen.ppt
(Fall dinner meeting)








Download all presentations (.zip)
PK/PD Modeling and Simulation for Compound Progression of Antiretroviral Agents - jeffrey-barrett.pdf

Statistical spectroscopy and global systems biology approaches in disease modeling - jeremy-nicholson.ppt

Small Molecule Analysis Using Diverse Separation Techniques Coupled to MicroelectrosprayMass Spectrometry - paul-vouros.pdf

Ionization Methods in MS - graham-cooks.pdf



2005





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Targeted Bioavailability - Mechanisms of Drug Tissue Distribution - elmquist.ppt

Hepatic Drug Transport - hoffmaster.pdf

PGx of Drug-Transporter Interactions - sadee.pdf

HT Approaches to AMS - skipper.pdf