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Events
     

NEDMDG Spring Meeting
     

Our NEDMDG Spring Meeting will be held on Wednesday, March 7, 2012 at the LE MERIDIEN
 
 

This meeting is sponsored by:
Absorption Systems

Absorption Systems, Exton, PA  USA
     
J. Scott Daniels, Ph.D.
Director, Drug Metabolism & Pharmacokinetics
Vanderbilt Center for Neuroscience Drug Discovery
Assistant Professor of Pharmacology
 
Vanderbilt University Medical Center
Nashville, TN (USA)
 

Entitled:
“Biotransformation of Novel mGlu5 Negative Allosteric Modulators: Enabling Academic Drug Discovery While Advancing Disposition Science”
     
Cocktail hour will begin at 5:30 PM, dinner at 6:30 PM and the presentation at 7:30 PM.
Please indicate your choice of entrée when making your reservation:
 

Crisp Skin Wing Tip Chicken Breast Parmesan Polenta, Grilled Asparagus, Creamy Leeks
OR

Mustard Crusted Salmon Puy Lentils, Grilled Zucchini, Champagne Beurre Blanc
OR

Mushroom Ravioli Roasted Tomatoes, Sweet Pea Cream Sauce
OR
If you need a Special Food Request - select 'Other' and contact: 
 

***The deadline for reservations and/or cancellations is 8 am, February 29, 2012***
 
The link for easy registration is:

https://www.events.org/nedmdg01/viewevent.aspx?id=40915
 
Please remember, when registering: After you have filled in the quantity of reservations to be made, in the 'Contact Information Section', make sure you enter the name, phone number, email address and most importantly the entree choice for each of the registrants. Use the drop down list under 'Meals' section (see sample below).
 
If you have any questions, please contact:
Jeanne Sherwood
781-935-5115, Ext. 2218
E-mail: Jeanne_Sherwood@bd.com

The Second International Transporter Consortium Workshop (ITCW2)
“Membrane Transporters in Drug Development: Best Practices and Future Directions”
Mon/Tues March 12/13, 2012
Gaylord National Convention Center (10min from DC)
As part of the ASCPT annual conference.
We have strived to compile a highly relevant program with a robust line-up of international scientific experts from industry, academia, and government.
This workshop will continue the themes of the first ITC workshop, as captured in the associated white paper (Nature Reviews Drug Discovery 9, 215-236 (2010)) which was the most cited publication of NRDD in 2010 (cf commentary in NRDD 11, p3 (2012)). The white paper fostered constructive dialog between academia, industry and regulators which helped to provide perspectives for the FDA draft DDI guidance. There will be an opportunity to hear first hand from the FDA as well as the EMA at this workshop. The second workshop aims to continue the ongoing discussion with sessions on emerging transporters (MATEs, MRP2, BSEP), expanding on in vitro and in vivo techniques (MALDI, cell systems), and highlighting the importance of considering intracellular concentrations, transporter kinetics, and PBPK when evaluating drug transport. There will also be an update from the digoxin/Pgp IC50 Pharma working group. The workshop will devote the final afternoon to presentations and discussions on regulatory and industry perspectives highlighting the impact of the white paper and regulatory guidances in drug development.
This is your opportunity to hear first hand relevant transporter related issues from your colleagues in industry, academia and regulatory authorities and to provide your insights and feedback on the white paper and guidances. We hope that the workshop will build on the dialog stimulated by the first workshop, solidify our current understanding, challenge our current thinking, and prepare us for the future so that we can better address those complex and important issues related to Drug Transporters. It is our intent to compile additional white papers based on these discussions.
There will also be 5 breakout sessions on relevant topics where there will be an opportunity for you to voice your opinion and contribute to our current understanding of these topics.
We also invite you to join us on Tuesday, March 14, 2012, 5:00 pm – 6:00 pm for a conversation on moving the ITC forward. This is your opportunity to provide input to the group as we plan for the future.
The ITCW2 Organizing Committee:

Kim Brouwer, Kate Hillgren, Keith Hoffmaster, Toshi Ishikawa, Dietrich Keppler, Donald Tweedie (Chair), Maciej Zamek-Gliszczynski, Lei Zhang.
Please register on line at http://www.ascpt.org/Home/GotoExpoLogic/tabid/9779/Default.aspx